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Priorities in Research Portfolios: Exploring the Need For upstream Research In cardiometabolic and Mental Health

Priorities in Research Portfolios: Exploring the Need For upstream Research In cardiometabolic and Mental Health

There is a debate on shifting research away from biomedical treatments towards health promotion and well-being. This study examines if research agendas are responsive to these demands in cardiometabolic and mental health.

Automated Detection of Poor-quality Data: Case Studies in Healthcare

Automated Detection of Poor-quality Data: Case Studies in Healthcare

The detection and removal of poor-quality data in a training set is crucial to achieve high-performing AI models. In healthcare, data can be inherently poor-quality due to uncertainty or subjectivity, but as is often the case, the requirement for data privacy restricts AI practitioners from accessing raw training data, meaning manual visual verification of private patient data is not possible. Here we describe a novel method for automated identification of poor-quality data, called Untrainable Data Cleansing. This method is shown to have numerous benefits including protection of private patient data; improvement in AI generalizability; reduction in time, cost, and data needed for training; all while offering a truer reporting of AI performance itself. Additionally, results show that Untrainable Data Cleansing could be useful as a triage tool to identify difficult clinical cases that may warrant in-depth evaluation or additional testing to support a diagnosis.

FDA Approves an Ebola Vaccine, Long in Development, for the First Time - STAT

FDA Approves an Ebola Vaccine, Long in Development, for the First Time - STAT

The vaccine, developed by Merck, protects against Zaire ebolaviruses, the species of the virus that has been the most common cause of Ebola outbreaks.

Dissecting Racial Bias in an Algorithm Used to Manage the Health of Populations

Dissecting Racial Bias in an Algorithm Used to Manage the Health of Populations

The U.S. health care system uses commercial algorithms to guide health decisions. Obermeyer et al. find evidence of racial bias in one widely used algorithm, such that Black patients assigned the same level of risk by the algorithm are sicker than White patients (see the Perspective by Benjamin). The authors estimated that this racial bias reduces the number of Black patients identified for extra care by more than half.

Zika: Researchers Are Learning More About The Long-Term Consequences For Children

Zika: Researchers Are Learning More About The Long-Term Consequences For Children

In the three years since it ended, the pandemic has become an object of obsession for scientists, who have published more than 6,000 research papers about it. What did they conclude?